Screen High Flux Liquid Handing System is to partition single nucleic acid template into separate reaction chambers and performs a single molecule quantification by PCR amplification and fluorescence signal detection. The digital PCR technology does not reply on neither Ct values nor standard calibration curves, and has extremely high sensitivity, precision, and excellent repeatability.
Automated Ngs
It is an absolute quantitative analysis technology that transcends real-time PCR. The DropX-2000 Droplet Digital PCR System puts this powerful technology in your hands, ready to unveil new worlds of research at previously unattainable levels.
DNA Research
We detected cfDNA somatic mutations in combination with protein markers to efficiently identify early stage HCC from asymptomatic HBsAg-seropositive individuals in a community population.
AFP And Ultrasonography
We designed an assay to profile multiple types of genetic variations in parallel so that 2 mL of plasma were sufficient to achieve high sensitivity in the detection of cfDNA mutations. The assay successfully identified four early-stage HCC cases (<3 cm) from 331 HBsAg (+) individuals who were negative based on screening with serum AFP and ultrasonography.
HCC
The positive predictive value was 17%, which was much higher than in previous studies. This paper shows that the combination of cfDNA and serum protein markers has significant promise for the early detection of HCC in the community population.
