The role and synthesis of indole-3-butyric acid

Functions 

Years of practice have proven that synthesized indole-3-butyric acid is a highly efficient, low-toxicity, highly active, broad-spectrum, pollution-free biochemical agent. It is an excellent plant growth regulator, rooting agent, and a growth promoter for melons and fruits that can significantly improve fruit setting rate.

Synthesis Method 

A method for synthesizing the plant growth regulator 3-indolebutyric acid, characterized by the following steps:

(1) At room temperature and pressure, salicylic acid is catalytically hydrogenated using a polymer hydrogenation catalyst; esterification is carried out using an organic superacid as a catalyst, wherein the salicylic acid reacts with ethanol... (1) The molar ratio of ethyl cyclohexylcarboxylate to aniline is 1:20 to 1:80;

(2) Oxidation reaction is carried out at 70℃ using a polymer oxidizing agent, with a molar ratio of ethyl cyclohexylcarboxylate to aniline of 1:1.5 to 1:2;

(3) Condensation reaction is carried out at -5℃ to 10℃, followed by reflux hydrolysis under alkaline conditions and acidification at room temperature, with a molar ratio of ethyl cyclohexanone-2-carboxylate to aniline of 1:1;

(4) Decarboxylation reaction is carried out by Fischer rearrangement and heating to 225℃ to 230℃.

This invention is a novel, environmentally friendly, and energy-saving process for synthesizing the plant growth regulator 3-indolebutyric acid, which uses inexpensive and readily available raw materials, operates under mild reaction conditions, has simple synthesis steps, and allows for the repeated use of polymer hydrogenation catalysts and oxidants, avoiding heavy metal pollution.