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SZ-WX
Senzhuo
Product Details:
Also known as sodium salt of sulfobutyl ether beta-cyclodextrin, it is a sodium salt obtained by the ethylation of beta-cyclodextrin under alkaline conditions with 1,4-butanedisulfonic acid ester. It is an anionic type highly water-soluble cyclodextrin derivative. It can effectively complex drug molecules to form non-covalent complexes, thereby improving the stability, water solubility, safety, reducing renal toxicity, alleviating hemolytic effects of drugs, controlling the release rate of drugs, masking unpleasant odors, etc.
| CAS | 182410-00-0 |
| MF | C70H119Na7O56S7 |
| MW | MW |
| EINECS | 1308068-626-2 |
| Melting Point | 202-204°C (dec.) |
Application:
1. Solubilization:
Neutral, positive and negative raw materials can effectively combine with sulfobutyl beta-cyclodextrin, thereby increasing the solubility of compounds with different solubilities in the raw material solution by 10 to 25,000 times.
2. Convenient administration:
Sulfobutyl beta-cyclodextrin has excellent biocompatibility and can be administered by injection, oral administration, eye, nose, topical application and inhalation.
3. Good safety:
Under normal circumstances, it can be rapidly and completely eliminated from the kidneys after administration. Safety data from in vitro experiments and acute, subacute and chronic toxicity studies in vivo have been provided, and it has been approved for use in human pharmaceutical preparations.
4.Good stability:
The interaction with sulfobutyl beta-cyclodextrin provides a beneficial protective environment for the raw materials in its lipophilic cavity, while the hydrophilic surface provides excellent water solubility for solubility and stability.
Storage:
25kg/drum
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