Dihexa CAS 1401708-83-5

MF： C27H44N4O5
MW： 504.66
CAS： 1401708-83-5

Appearance:White powder

Package:10g/bottle 10g/bag

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Brand:
Senzhuo

Product Description

Melting point	>209°C (dec.)
Boiling point	866.2±65.0 °C(Predicted)
density	1.111±0.06 g/cm3(Predicted)
storage temp.	Hygroscopic, Refrigerator, under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	9.83±0.15(Predicted)
color	White to Off-White

Application:

Dihexa, an oligopeptide drug, is an orally active and blood-brain barrier-permeable angiotensin IV analog. Dihexa binds to hepatocyte growth factor (HGF) with high affinity (Kd=65 pM) and potentiates its activity at its receptor, c-Met. Dihexa exhibits excellent antidementia activity and improves cognitive function in animal models. Dihexa may have therapeutic potential as a treatment Alzheimer’s disease.