18-Crown-6 CAS 17455-13-9

Details

Product name： 18-Crown-6
CAS： 17455-13-9
MF： C12H24O6
MW： 264.32
EINECS： 241-473-5
Appearance： White powder

Specification

Application

It can form stable complexes with various metal salts, ammonium salts, organic cationic compounds, etc. By utilizing this property, various salts can be dissolved in organic solvents. Crown ethers can chelate cations, and because of the outward-facing organic genes, they can also form complexes and are soluble in non-polar organic solvents. At this time, the unsolvated anions exist in the solvent as naked anions, so they are extremely active. Crown ethers can dissolve alkali metals and organic alkali metal compounds in organic solvents. Therefore, they are widely used in organic synthesis, optical resolution, heavy metal chelation, separation, analysis, and physiologically active medicine, biochemistry, etc. For example, as a phase transfer catalyst, many reactions that are difficult to react or even do not occur under traditional conditions can be carried out smoothly. This type of reaction has a fast reaction rate, simple conditions, convenient operation, and high yield. For example, the yield of the condensation reaction of benzoin in aqueous solution is extremely low. If 7% crown ether is added to the aqueous solution, benzoin with a yield of 78% can be obtained. This reaction can also be carried out in benzene (or acetonitrile). Although potassium cyanide is insoluble in benzene, if 18-crown-6 is added, not only can the reaction occur, but the yield can be as high as 95%. Toxicity of 18-crown-6: The oral lethal dose for rats is 300 mg/kg. It is irritating to eyes and skin.

Storage

Store below +30°C.